SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM 8-K


                Current Report Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934



       Date of Report (Date of earliest event reported) December 24, 1998
                                                       -------------------


                             TECHNICLONE CORPORATION
              -----------------------------------------------------
              (Exact name of registrant a specified in its Charter)


       Delaware                        0-17085                    95-3698422  
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(State or other jurisdiction         (Commission                (IRS Employer
   of incorporation)                 File Number)            Identification No.)



         14282 Franklin Avenue, Tustin, California      92780-7017         
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         (Address of principal executive offices)       (Zip Code)



Registrant's telephone number, including area code        (714) 508-6000        
                                                     -----------------------


                                 Not Applicable
          -------------------------------------------------------------
          (Former name or former address, if changed since last report)







ITEM 2.  ACQUISITION OR DISPOSITION OF ASSETS


         On December 24, 1998, Techniclone Corporation, a Delaware corporation
(the "Company"), completed the sale/leaseback of its two corporate facilities
totaling 47,500 square feet with TNCA, LLC, an unrelated Delaware limited
liability company, for an aggregate sale price of $6,100,000. Consideration
received by the Company includes a cash payment of $4,175,000 and receipt of a
Note totaling $1,925,000 issued by TCNA Holding, LLC, a Delaware limited
liability company and parent of TNCA, LLC. The Note Receivable bears 7%
interest, is payable monthly based on a 20-year amortization, and is due upon
the earlier to occur of: the sale of the property or the end of the initial
lease term (12 years). The consideration received by the Company for the
sale/leaseback of the facilities was determined pursuant to arm's-length
negotiation between the Company and the buyer/landlord, taking into account the
value of similar facilities in the same geographic region, comparable
transactions, and the market for such facilities generally.

         The leaseback is a Triple Net Lease, wherein the lessee (the Company)
is responsible for all expenses incurred in the maintenance of the building
including property taxes and insurance. The Company negotiated a twelve-year
lease with two five-year extension options. The initial base rent is $56,250 per
month, with 3.35% rent increases at two year intervals. Concurrently, the
Company borrowed $200,000 from TNCA Holdings, LLC pursuant to a 7% note payable
over a three year period. The net cash received by the Company, reduced by the
amounts required to satisfy existing mortgages (totaling $1,942,000), expenses
of the sale, lease deposits, prorated rent and the increase of the $200,000
borrowing, amounted to $1,921,000.

         The Company's continued existence is dependent on obtaining funding for
operations from all possible sources. As such, the Company entered into this
sale/leaseback transaction in order to obtain the net cash proceeds mentioned
above. Under the terms of the sale/leaseback, the Company recovered its original
building purchase price and substantially all of its investment in facility
improvements. The remaining unrecovered investment resulted in a non-cash charge
of approximately $730,000 based on the excess of the net book value of the
sale/leaseback assets sold over the net consideration received after commissions
and other transaction costs which totaled approximately $256,000. The Company's
new management has revised its manufacturing strategy from one of investing in
facilities and equipment to produce potential future products in-house to having
this production performed by outside contract manufacturers. As a result of this
decision, the Company recorded a non-cash charge of approximately $440,000
related to the write-off of manufacturing facility design costs capitalized in
the prior fiscal year which will not be utilized. The total of these non-cash
charges recorded in December 1998 was approximately $1,170,000.


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ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS

(a)      Financial Statements of Business Acquired.   Not applicable.
         ------------------------------------------

(b)      Pro Forma Financial Information.   Not applicable.
         --------------------------------

(c)      Exhibits.
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               99.1 Text of Press Release dated December 28, 1998.


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                                    SIGNATURE


         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly cause this report to be signed on its behalf by the
undersigned hereunto duly authorized.

Date: January 6, 1998               TECHNICLONE CORPORATION


                            By: /S/ STEVEN C. BURKE 
                               -----------------------------   
                               Steven C. Burke, Chief Financial Officer


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                                                                    EXHIBIT 99.1


             TECHNICLONE CONSUMMATES $6.1 MILLION SALE/LEASEBACK OF
                              CORPORATE FACILITIES



    -Company Receives $1.9 Million in Net Proceeds and a Note Receivable for
                                 $1.9 Million-

TUSTIN, CA.-DECEMBER 28, 1998-TECHNICLONE CORPORATION (NASDAQ: TCLN) a developer
of leading-edge unique therapeutics for the advanced treatment of cancer,
announced today that it has consummated the sale/leaseback of its two corporate
facilities totaling 47,500 square feet for an aggregate sales price of
$6,100,000.

Consideration received by the Company includes a cash payment of $4,175,000 and
receipt of a Note totaling $1,925,000. The Note Receivable bears 7% interest, is
payable monthly based on 20 year amortization, and is due upon the earlier to
occur: sale of the property or the end of the initial lease term (12 years).

The leaseback is a Triple Net Lease, wherein the lessee (Techniclone) is
responsible for all expenses incurred in the maintenance of the building
including property taxes and insurance. The Company negotiated a twelve-year
lease with two five-year extension options.
The initial basic rent is $56,250 per month, with 3.35% rent increases at two
year intervals.

Concurrently, the Company borrowed $200,000 from the buyer/landlord pursuant to
a 7% note payable over a three year period.

The net cash received by the Company, reduced by the amounts required to satisfy
existing mortgages (totaling $1,942,000), expenses of the sale, lease deposits,
prorated rent and the increase of the $200,000 borrowing, amounted to
$1,921,000.

Steven C. Burke, Chief Financial Officer stated, "The Company is pleased to have
closed this transaction which provides Techniclone with additional operating
capital as we fulfill our needs for expanded clinical trial activity and
scale-up in preparation for commercialization."

Safe Harbor Statement: This release may contain certain forward-looking
statements that are made pursuant to the safe harbor provisions of the Private
Securities Litigation Reform Act of 1995. Actual events or results may differ
from the Company's expectations as a result of risk factors discussed in
Techniclone's reports on file with the U.S. Securities and Exchange Commission,
including, but not limited to, the Company's report on Form 10Q for the quarter
ended July 31, 1998 and Form 10K for the year ended April 30, 1998.


                                       -5-




Company Overview: Techniclone Corporation is engaged in the research and
development of unique therapeutics for the treatment of cancer. The Company
utilizes innovative targeting technologies to develop products capable of
destroying cancerous tumors throughout the body.

Presently in Phase II clinical testing, the Company's Tumor Necrosis Therapy
(TNT) is designed to deliver high doses of radiation directly to the core of the
tumor while causing minimal damage to surrounding tissue. Oncolym(R), a therapy
for the treatment of advanced Non-Hodgkin's B-Cell Lymphoma, is currently
undergoing Phase II/III human testing.

The Company is also developing two additional technologies for the treatment of
solid tumors, Vasopermeation Enhancement Agents (VEA) and Vascular Targeting
Agents (VTA). VEAs act on tumors to increase the concentration of conventional
chemotherapy in the tumor site while VTAs attach to tumor blood vessels creating
a blood clot which kills the tumor by eliminating its oxygen and nutrient
supply. Additional information on the Company and its products can be found at
www.techniclone.com.


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